The Tigers had four players reach double digits, led by Ryan VanCauwenbaugh and Aaron Casey with 13 points each.
Huron hit 26-of-54 shots from inside the arc and held a 53-26 rebounding advantage.
The Tigers outscored the Streaks 40-21 in the second half.
D'Maja Jordan led Sandusky with 12 points.
Read more in Thursday's Sandusky Register.